Research articles:

2015

• An information-based approach to change-point analysis with applications to biophysics and cell biology
  Paul A. Wiggins.
  Biophysical Journal 109(2):346-354

• High-throughput cell-cycle imaging opens new doors for discovery
  Nathan J. Kuwada, Beth Traxler, and Paul A. Wiggins.
  Current Genetics 1-4

• Kin cell lysis is a danger signal that activates antibacterial pathways of Pseudomonas aeruginosa
  Michele LeRoux, Robin L. Kirkpatrick, Elena I. Montauti, Bao Q. Tran, S. Brook Peterson, Brittany N. Harding, John C. Whitney, Alistair B. Russell, Beth Traxler, Young Ah Goo, David R. Goodlett, Paul A. Wiggins, and Joseph D. Mougous.
  eLife 2015;4:e05701

• Physical modeling of chromosome segregation in Escherichia coli reveals impact of force and DNA relaxation
  Thomas J. Lampo, Nathan J. Kuwada, Paul A. Wiggins, and Andrew J. Spakowitz.
  Biophysical Journal 108(1):146-153
  
  
  Featured as New and Notable with commentary:
  The Ghost in the Machine: Is the Bacterial Chromosome a Phantom Chain?
  Jian Liu, Biophysical Journal 108(1):20-21

• Genome-scale quantitative characterization of bacterial protein localization dynamics throughout the cell cycle
  Nathan J. Kuwada, Beth Traxler, and Paul A. Wiggins.
  Molecular Microbiology 95(1):64-79
  
  
  Online database for Localizome data can be found here.

2014

• Cytoplasmic dynamics reveals two modes of nucleoid-dependent mobility
  Stella Stylianidou, Nathan J. Kuwada, and Paul A. Wiggins.
  Biophysical Journal 107(11):2684-2692

• RNA Mango aptamer-fluorophore: A bright, high-affinity complex for RNA labeling and tracking
  Elena V. Dolgosheina, Sunny CY Jeng, Shanker Shyam S. Panchapakesan, Razvan Cojocaru, Patrick SK Chen, Peter D. Wilson, Nancy Hawkins, Paul A. Wiggins, and Peter J. Unrau.
  ACS Chemical Biology

• Unidirectional P-Body transport during the yeast cell cycle
  Cecilia Garmendia-Torres, Alexander Skupin, Sean A. Michael, Pekka Ruusuvuori, Nathan J. Kuwada, Didier Falconnet, Gregory A. Cary, Carl Hansen, Paul A. Wiggins, Aimée M. Dudley.
  PloS ONE 9(6):e99428

• Persistent super-diffusive motion of Escherichia coli chromosomal loci
  Avelino Javer, Nathan J. Kuwada, Zhicheng Long, Vincenzo G. Benza, Kevin D. Dorfman, Paul A. Wiggins, Pietro Cicuta, and Marco Cosentino Lagomarsino.
  Nature Communications 5

2013

• c-di-GMP heterogeneity is generated by the chemotaxis machinery to regulate flagellar motility
  Bridget R. Kulasekara, Cassandra Kamischke, Hemantha D. Kulasekara, Matthias Christen, Paul A. Wiggins, Samuel I. Miller.
  eLife 2:e01402

• Estimating podocyte number and density using a single histologic section.
  Manhusudan Venkatareddy, Su Wang, Yan Yang, Sanjeevkumar Patel, Larysa Wickman, Ryuzoh Nishizono, Mahboob Chowdhury, Jeffrey Hodgin, Paul A. Wiggins, and Roger C. Wiggins.
  Journal of the American Society of Nephrology 25:1118-1129

• Mapping the driving forces of chromosome structure and segregation in Escherichia coli.
  Nathan J. Kuwada, Keith C. Cheveralls, Beth Traxler, and Paul A. Wiggins.
  Nucleic Acids Research 41:7370-7377

• Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.
  Alistair B. Russell, Michele LeRoux, Kristina Hathazi, Danielle M. Agnello, Takahiko Ishikawa, Paul A. Wiggins, Sun Nyunt Wai, and Joseph D. Mougous.
  Nature 496:508-512

• Calculator for conformational statistics of DNA and applications to high-curvature bending.
  Brian C. Ross and Paul A. Wiggins.
  Physical Review E 87:032707.

2012

• Quantitative single-cell characterization of bacterial interactions reveals type VI secretion is a double-edged sword.
  Michele LeRoux, Justin A. De Leon, Nathan J. Kuwada, Alistair B. Russell, Delia Pinto-Santini, Rachel D. Hood, Danielle M. Agnello, Stephen M. Robertson, Paul A. Wiggins, and Joseph D. Mougous.
  PNAS 109:19804-19809.

• Multidisciplinary perspectives on bacterial genome organization and dynamics
  Remus T. Dame, Olivier Espéli, David C. Grainger, and Paul A. Wiggins.
  Molecular Microbiology 86:1023-1030.

• A single-molecule Hershey-Chase experiment.
  David Van Valen, David Wu, Yi-Ju Chen, Hannah Tuson, Paul Wiggins, and Rob Phillips.
  Current Biology 22:1339-1343.

• Measuring chromosome conformation with degenerate labels.
  Brian C. Ross and Paul A. Wiggins.
  Physical Review E 86:011918.

• Surface sensing and lateral subcellular localization of WspA, the receptor in a chemosensory-like system leading to c-di-GMP production.
  Jennifer R. O'Connor, Nathan J. Kuwada, Varisa Huangyutitham, Paul A. Wiggins, and Caroline S. Harwood.
  Molecular Microbiology 86:720-729.

• A model for Escherichia coli chromosome packaging supports transcription factor-induced DNA domain formation.
  Miriam Fritsche, Songling Li, Dieter W. Heermann, and Paul A. Wiggins.
  Nucleic Acids Research 40:972-980.

2011

• Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.
  ChristineL Chaffer, Ines Brueckmann, Christina Scheel, AliciaJ Kaestli, Paul A. Wiggins, Leonardo O. Rodrigues, Mary Brooks, Ferenc Reinhardt, Ying Su, Kornelia Polyak, Lisa M Arendt, Charlotte Kuper- wasser, Brian Bierie, and RobertA Weinberg.
  PNAS 108:1950-7955

2010

• Strong intranucleoid interactions organize the Escherichia coli chromosome into a nucleoid filament.
  Paul A. Wiggins, Keith C. Cheveralls, Joshua S. Martin, Robert Lintner, and Jan ́e Kondev.
  PNAS 107:4991-4995

2009

• Protein mediated bridging motifs: a key mechanism in biopolymer organization.
  Paul A. Wiggins, Remus Th Dame, Maarten C. Noom, Gijs J. Wuite.
  Biophysical Journal 97:1997-2003 (Featured Article)

• Emerging roles for lipids in shaping membrane-protein function.
  Rob Phillips, Tristan Ursell, Paul Wiggins, Pierre Sens.
  Nature. Review.

2008

• Membrane shape as a reporter for applied forces.. Lee HJ, Peterson EL, Phillips R, Klug WS, Wiggins PA. Proc Natl Acad Sci U S A.

  Commentary:

  • Membranes: Shaping biological matter. Frolov VA, Zimmerberg J.Nature Materials. 8(3) 173-174. (2009).

• Mechanosensation in Mechanosensitivity in Cells and Tissues 1: Mechanosensitive Ion Channels
  T. Ursell, J. Kondev, D. Reeves, P. Wiggins, and R. Phillips. The Role of Lipid Bilayer Mechanics in edited by A. Kamkin and I. Kiseleva, Springer-Verlag, Berlin, Review.

2007

• Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity.
  Garcia HG, Grayson P, Han L, Inamdar M, Kondev J, Nelson PC, Phillips R, Widom J, Wiggins
  PA.Biopolymers

2006

• High flexibility of DNA on short length scales probed by atomic force microscopy.
  Wiggins PA, van der Heijden T, Moreno-Herrero F, Spakowitz A, Phillips R, Widom J, Dekker C, Nelson PC.
  Nat Nanotechnol.

  Commentary:

  • Polymer physics: DNA off the Hooke. Nat Nanotechnol. 1(2) 100-1. (2006)

  • Physicsb in the cell: Spring theory. Podgornik R, Brendan Maher. Nature 448, 984-986.

• Generalized theory of semiflexible polymers.
  Wiggins PA, Nelson PC.
  Phys Rev E Stat Nonlin Soft Matter Phys.

• Exact theory of kinkable elastic polymers.
  P. Wiggins, R. Phillips & P. Nelson.
  (PRE 013501, cond- mat/0409003).

2005

• Membrane-protein interactions in mechanosensitive channels.
  P. Wiggins & R. Phillips.
  Biophys. J., 88
  

2004

• Analytic models for mechanotransduction: Gating a mechanosensitive channel
  P. Wiggins & R. Phillips.
  Proc. Nat. Acad. Sci.

2000

• Tidal Interactions Between a Fluid Star and a Kerr Black Hole in Circular Orbit
  P. Wiggins & D. Lai
  Astrophys. J.

1998

• Measuring the Elastic Modulus of Small Tissue Samples
  R.Q. Erkamp, P. Wiggins, A.R. Skovoroda, S.Y. Emelianov, & M. O'Donnell.
  Ultrasonic Imaging